Beta-mangostin demonstrates apoptogenesis in murine leukaemia (WEHI-3) cells in vitro and in vivo

• Главные авторы: Fatima Abdelmutaal Ahmed Omer (Автор), Najihah Mohd Hashim (Автор), Mohamed Yousif Ibrahim (Автор), Abdulmannan F. Aldoubi (Автор), Pouya Hassandarvish (Автор), Firouzeh Dehghan (Автор), Noraziah Nordin (Автор), Hamed Karimian (Автор), Landa Zeenelabdin Ali Salim (Автор), Mahmood Ameen Abdulla (Автор), Karim Al-Jashamy (Автор), Syam Mohan (Автор)
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• Опубликовано: BMC, 2017-07-01T00:00:00Z.
• Предметы: article
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Abstract Background Beta-mangostin (BM) is a xanthone-type of natural compound isolated from Cratoxylum arborescens. This study aimed to examine the apoptosis mechanisms induced by BM in a murine monomyelocytic cell line (WEHI-3) in vitro and in vivo. Methods A WEHI-3 cell line was used to evaluate...