Beta-mangostin demonstrates apoptogenesis in murine leukaemia (WEHI-3) cells in vitro and in vivo

• Main Authors: Fatima Abdelmutaal Ahmed Omer (Author), Najihah Mohd Hashim (Author), Mohamed Yousif Ibrahim (Author), Abdulmannan F. Aldoubi (Author), Pouya Hassandarvish (Author), Firouzeh Dehghan (Author), Noraziah Nordin (Author), Hamed Karimian (Author), Landa Zeenelabdin Ali Salim (Author), Mahmood Ameen Abdulla (Author), Karim Al-Jashamy (Author), Syam Mohan (Author)
• Format: Book
• Published: BMC, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Beta-mangostin (BM) is a xanthone-type of natural compound isolated from Cratoxylum arborescens. This study aimed to examine the apoptosis mechanisms induced by BM in a murine monomyelocytic cell line (WEHI-3) in vitro and in vivo. Methods A WEHI-3 cell line was used to evaluate...