MMPP promotes adipogenesis and glucose uptake via binding to the PPARγ ligand binding domain in 3T3-L1 MBX cells

• Main Authors: Na-Yeon Kim (Author), Chae-Min Lim (Author), Hyo-Min Park (Author), Jinju Kim (Author), Thu-Huyen Pham (Author), Young Yang (Author), Hee Pom Lee (Author), Jin Tae Hong (Author), Do-Young Yoon (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Peroxisome proliferator-activated receptor-gamma (PPARγ) is a transcription factor involved in adipogenesis, and its transcriptional activity depends on its ligands. Thiazolidinediones (TZDs), well-known PPARγ agonists, are drugs that improve insulin resistance in type 2 diabetes. However, TZDs are...