Mechanistic Modeling of a Novel Oncolytic Virus, V937, to Describe Viral Kinetic and Dynamic Processes Following Intratumoral and Intravenous Administration

• প্রধান লেখক: Zinnia P. Parra-Guillen (লেখক), Tomoko Freshwater (লেখক), Youfang Cao (লেখক), Kapil Mayawala (লেখক), Sara Zalba (লেখক), Maria J. Garrido (লেখক), Dinesh de Alwis (লেখক), Iñaki F. Troconiz (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

V937 is an investigational novel oncolytic non-genetically modified Kuykendall strain of Coxsackievirus A21 which is in clinical development for the treatment of advanced solid tumor malignancies. V937 infects and lyses tumor cells expressing the intercellular adhesion molecule I (ICAM-I) receptor....