HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material

• Main Authors: William Ottestad (Author), Ingrid N. Rognes (Author), Erlend Skaga (Author), Cassandra Frisvoll (Author), Guttorm Haraldsen (Author), Torsten Eken (Author), Peter Lundbäck (Author)
• Format: Book
• Published: BMC, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background HMGB1 is a mediator of systemic inflammation in sepsis and trauma, and a promising biomarker in many diseases. There is currently no standard operating procedure for pre-analytical handling of HMGB1 samples, despite that pre-analytical conditions account for a substantial part of...