HMGB1 concentration measurements in trauma patients: assessment of pre-analytical conditions and sample material

• Главные авторы: William Ottestad (Автор), Ingrid N. Rognes (Автор), Erlend Skaga (Автор), Cassandra Frisvoll (Автор), Guttorm Haraldsen (Автор), Torsten Eken (Автор), Peter Lundbäck (Автор)
• Формат: ‌
• Опубликовано: BMC, 2019-12-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Background HMGB1 is a mediator of systemic inflammation in sepsis and trauma, and a promising biomarker in many diseases. There is currently no standard operating procedure for pre-analytical handling of HMGB1 samples, despite that pre-analytical conditions account for a substantial part of...