Dosage Adjustment of Irinotecan in Patients with UGT1A1 Polymorphisms: A Review of Current Literature

Objective: To review available literature regarding pharmacogenomics (PGx) effects on the metabolism of irinotecan by the UGT1A1 gene and the resulting dose adjustments based on PGx genetic variant. Summary: Irinotecan is a chemotherapy agent commonly used in treatment of various cancers such as met...

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Main Authors: Lia Argevani (Author), Caren Hughes (Author), Michael J. Schuh (Author)
Format: Book
Published: University of Minnesota Libraries Publishing, 2020-08-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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