Photodynamic Opening of the Blood-Brain Barrier and the Meningeal Lymphatic System: The New Niche in Immunotherapy for Brain Tumors

• Main Authors: Oxana Semyachkina-Glushkovskaya (Author), Andrey Terskov (Author), Alexander Khorovodov (Author), Valeria Telnova (Author), Inna Blokhina (Author), Elena Saranceva (Author), Jürgen Kurths (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Photodynamic therapy (PDT) is a promising add-on therapy to the current standard of care for patients with glioblastoma (GBM). The traditional explanation of the anti-cancer PDT effects involves the PDT-induced generation of a singlet oxygen in the GBM cells, which causes tumor cell death and microv...