Dimeric and polymeric IgA, but not monomeric IgA, enhance the production of IL-6 by human renal mesangial cells

Depositions of IgA in the renal glomerular mesangial area are a hallmark of IgA nephropathy, and are thought to be crucial for the onset of inflammation processes in IgA nephropathy. In this report we show that human mesangial cells (MC) in vitro bind IgA and that binding of IgA enhances the product...

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Bibliographic Details
Main Authors: T. J. F. Reterink (Author), W. E. M. Schroeijers (Author), L. A. van Es (Author), M. R. Daha (Author)
Format: Book
Published: Hindawi Limited, 1996-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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