Assay of empagliflozin tablets by a stability-indicating micellar electrokinetic chromatography method and cytotoxicity study of degraded samples

• Main Authors: Pauline Trindade Biscaino (Author), Ana Paula Christ (Author), Daniele Rubert Nogueira Librelotto (Author), Clarice Madalena Bueno Rolim (Author), Andréa Inês Horn Adams (Author)
• Format: Book
• Published: Universidade de São Paulo, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The first method by micellar electrokinetic chromatography (MEKC) for the determination of empagliflozin in tablets was developed and validated following the ICH guidelines. The separation was achieved in a fused silica capillary with 50 µm x 40 cm (inner diameter x effective length) at 28 ºC, +28 k...