A randomized, multicenter trial assessing the effects of rapastinel compared to ketamine, alprazolam, and placebo on simulated driving performance

• Päätekijät: Shengfang Su (Tekijä), Gary Kay (Tekijä), Thomas Hochadel (Tekijä), Jonathan Rojo (Tekijä), J. Christopher Stein (Tekijä), Ramesh Boinpally (Tekijä), Antonia Periclou (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wiley, 2022-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract N‐methyl‐D‐aspartate ionotropic glutamatergic receptor (NMDAR) modulators, including rapastinel and ketamine, elicit rapid and sustained antidepressant responses in patients with treatment‐resistant major depressive disorder. This phase I, randomized, multicenter, placebo‐controlled, five‐p...