Design, synthesis, and bio-evaluation of new isoindoline-1,3-dione derivatives as possible inhibitors of acetylcholinesterase

• Main Authors: Motahareh Hassanzadeh (Author), Farshid Hassanzadeh (Author), Ghadam Ali khodarahmi (Author), Mahbobe Rostami (Author), Fateme Azimi (Author), Hamid Nadri (Author), Farshad Homayouni Moghadam (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and purpose: Alzheimer's disease is considered one of the lead causes of elderly death around the world. A significant decrease in acetylcholine level in the brain is common in most patients with Alzheimer's disease, therefore acetylcholinesterase (AChE) inhibitors such as donep...