Characterization of novel isoforms and evaluation of <it>SNF2L/SMARCA1 </it>as a candidate gene for X-linked mental retardation in 12 families linked to Xq25-26

• Main Authors: Lavigne Paul (Author), Todd Matthew AM (Author), Lazzaro Maribeth A (Author), Vallee Dominic (Author), De Maria Adriana (Author), Picketts David J (Author)
• Format: Book
• Published: BMC, 2008-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Mutations in genes whose products modify chromatin structure have been recognized as a cause of X-linked mental retardation (XLMR). These genes encode proteins that regulate DNA methylation (<it>MeCP2</it>), modify histon...