Autologous engineered T cell receptor therapy in advanced cancer

• المؤلفون الرئيسيون: Apostolia M. Tsimberidou (مؤلف), Mehmet A. Baysal (مؤلف), Abhijit Chakraborty (مؤلف), Borje S. Andersson (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

ABSTRACTTo overcome challenges associated with adoptive cell therapy (ACT), we developed a personalized autologous T-cell therapy program. Patients with advanced cancer with HLA-A *02:01 allele and tumor expression of PRAME, MAGEA1, MAGEA4, MAGEA8, NY-ESO-1, COL6A3 exon 6, MXRA5, and/or MMP1 underwe...