β2-and β3-Adrenergic Receptors Contribute to Cancer-Evoked Pain in a Mouse Model of Osteosarcoma via Modulation of Neural Macrophages

• Main Authors: Gennaro Bruno (Author), Francesco De Logu (Author), Daniel Souza Monteiro de Araujo (Author), Angela Subbiani (Author), Federica Lunardi (Author), Sofia Rettori (Author), Romina Nassini (Author), Claudio Favre (Author), Maura Calvani (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The mechanisms involved in the development and maintenance of cancer pain remain largely unidentified. Recently, it has been reported that β-adrenergic receptors (β-ARs), mainly β2-and β3-ARs, contribute to tumor proliferation and progression and may favor cancer-associated pain and neuroinflammatio...