Induction of Heme Oxygenase-1 Inhibits Monocyte Chemoattractant Protein-1 mRNA Expression in U937 Cells

• Main Authors: Tomoki Shokawa (Author), Masao Yoshizumi (Author), Hideya Yamamoto (Author), Shinji Omura (Author), Mamoru Toyofuku (Author), Yoshito Shimizu (Author), Michinori Imazu (Author), Nobuoki Kohno (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: Heme oxygenase-1 (HO-1) is a stress-inducible isoform of HO with potential cytoprotective effects. Monocyte activation/migration mediated by monocyte chemoattractant protein-1 (MCP-1) is one of the earliest and important events in the pathogenesis of atherosclerosis. We examined the effec...