Alteration of Pharmacokinetics of Grepafloxacin in Type 2 Diabetic Rats

• Main Authors: Meguho Watanabe (Author), Masaki Kobayashi (Author), Jiro Ogura (Author), Natsuko Takahashi (Author), Hiroaki Yamaguchi (Author), Ken Iseki (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. Patients with type 2 diabetes are generally treated with various pharmacological compounds and are exposed to a high risk of drug-drug interactions. However, alterations of pharmacokinetics in a type 2 diabetes model have been obscure. The present study was undertaken to investigate the eff...