<i>Mycobacterium tuberculosis</i> H₂S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility

• Main Authors: Tafara T. R. Kunota (Author), Md. Aejazur Rahman (Author), Barry E. Truebody (Author), Jared S. Mackenzie (Author), Vikram Saini (Author), Dirk A. Lamprecht (Author), John H. Adamson (Author), Ritesh R. Sevalkar (Author), Jack R. Lancaster (Author), Michael Berney (Author), Joel N. Glasgow (Author), Adrie J. C. Steyn (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

H₂S is a potent gasotransmitter in eukaryotes and bacteria. Host-derived H₂S has been shown to profoundly alter <i>M. tuberculosis</i> (<i>Mtb</i>) energy metabolism and growth. However, compelling evidence for endogenous producti...