Micro-PET Imaging Demonstrates 3-O-β-D-Glucopyranosyl Platycodigenin as an Effective Metabolite Affects Permeability of Cell Membrane and Improves Dosimetry of [18F]-Phillygenin in Lung Tissue

• Main Authors: Fukui Shen (Author), Wenbo Wu (Author), Man Zhang (Author), Xiaoyao Ma (Author), Qingxin Cui (Author), Zhongyao Tang (Author), Hao Huang (Author), Tiantian Tong (Author), Leefong Yau (Author), Zhihong Jiang (Author), Yuanyuan Hou (Author), Gang Bai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Platycodon grandiflorum, as a traditional medicinal plant, is commonly used in the treatment of pulmonary disease. Platycodon saponins are proposed as active ingredients. However, the role of secondary saponin metabolites (SSM) in the traditional use of Platycodon has not yet been fully clarified. I...