2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammatory Activity

• Үндсэн зохиолчид: Juan Martín-López (Зохиогч), Sandra Codony (Зохиогч), Clara Bartra (Зохиогч), Christophe Morisseau (Зохиогч), María Isabel Loza (Зохиогч), Coral Sanfeliu (Зохиогч), Bruce D. Hammock (Зохиогч), José Brea (Зохиогч), Santiago Vázquez (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2021-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The pharmacological inhibition of soluble epoxide hydrolase (sEH) has been suggested as a potential therapy for the treatment of pain and inflammatory diseases through the stabilization of endogenous epoxyeicosatrienoic acids. Numerous potent sEH inhibitors (sEHI) have been developed, however many c...