Extracorporeal immune therapy with immobilized agonistic anti-Fas antibodies leads to transient reduction of circulating neutrophil numbers and limits tissue damage after hemorrhagic shock/resuscitation in a porcine model

• Main Authors: Bitu-Moreno José (Author), Baltes Jessica (Author), Sadek Sarah (Author), Ott Annina (Author), Witte Ingo (Author), Sager Martin (Author), Paunel-Görgülü Adnana (Author), Altrichter Jens (Author), Lögters Tim T (Author), Schek Alberto (Author), Müller Wolfram (Author), Jeri Teresa (Author), Windolf Joachim (Author), Scholz Martin (Author)
• Format: Book
• Published: BMC, 2010-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Hemorrhagic shock/resuscitation is associated with aberrant neutrophil activation and organ failure. This experimental porcine study was done to evaluate the effects of Fas-directed extracorporeal immune therapy with a leukocyte inhi...