Epigallocatechin-3-Gallate (EGCG)-Inducible SMILE Inhibits STAT3-Mediated Hepcidin Gene Expression

• Main Authors: Yu-Ji Kim (Author), Ki-Sun Kim (Author), Daejin Lim (Author), Dong Ju Yang (Author), Jae-Il Park (Author), Ki Woo Kim (Author), Jae-Ho Jeong (Author), Hueng-Sik Choi (Author), Don-Kyu Kim (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatic peptide hormone hepcidin, a key regulator of iron metabolism, is induced by inflammatory cytokine interleukin-6 (IL-6) in the pathogenesis of anemia of inflammation or microbial infections. Small heterodimer partner-interacting leucine zipper protein (SMILE)/CREBZF is a transcriptional corep...