A phase I study of a dual PI3-kinase/mTOR inhibitor BEZ235 in adult patients with relapsed or refractory acute leukemia
Abstract Background Combined inhibition of phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR) complexes may be an efficient treatment for acute leukemia. The primary objective of this phase I single center open label study was to determine the maximum tolerated dose (M...
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Autors principals: | , , , , , , , , , , , , |
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Format: | Llibre |
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BMC,
2020-09-01T00:00:00Z.
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Internet
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A1234.567 |
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Còpia 1 | Disponible |