NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity

• Main Authors: Karen Nørgaard Nielsen (Author), Julia Peics (Author), Tao Ma (Author), Iuliia Karavaeva (Author), Morten Dall (Author), Sabina Chubanava (Author), Astrid L. Basse (Author), Oksana Dmytriyeva (Author), Jonas T. Treebak (Author), Zachary Gerhart-Hines (Author)
• Format: Book
• Published: Elsevier, 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The ability of adipose tissue to expand and contract in response to fluctuations in nutrient availability is essential for the maintenance of whole-body metabolic homeostasis. Given the nutrient scarcity that mammals faced for millions of years, programs involved in this adipose plasticit...