Identification of Novel Aryl Carboxamide Derivatives as Death-Associated Protein Kinase 1 (DAPK1) Inhibitors with Anti-Proliferative Activities: Design, Synthesis, In Vitro, and In Silico Biological Studies

Identification of Novel Aryl Carboxamide Derivatives as Death-Associated Protein Kinase 1 (DAPK1) Inhibitors with Anti-Proliferative Activities: Design, Synthesis, In Vitro, and In Silico Biological Studies

Death-associated protein kinase 1 (DAPK1) is a serine/threonine protein kinase involved in diverse fundamental cellular processes such as apoptosis and autophagy. DAPK1 isoform plays an essential role as a tumor suppressor and inhibitor of metastasis. Consequently, DAPK1 became a promising target pr...

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Main Authors: Ahmed Elkamhawy (Author), Sora Paik (Author), Eslam M. H. Ali (Author), Ahmed H. E. Hassan (Author), So Jin Kang (Author), Kyeong Lee (Author), Eun Joo Roh (Author)
Format: Book
Published: MDPI AG, 2022-08-01T00:00:00Z.
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