Dynamic Modeling of Mitochondrial Membrane Potential Upon Exposure to Mitochondrial Inhibitors

• Main Authors: Huan Yang (Author), Wanda van der Stel (Author), Randy Lee (Author), Caroline Bauch (Author), Sam Bevan (Author), Paul Walker (Author), Bob van de Water (Author), Erik H. J. Danen (Author), Joost B. Beltman (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitochondria are the main bioenergetic organelles of cells. Exposure to chemicals targeting mitochondria therefore generally results in the development of toxicity. The cellular response to perturbations in cellular energy production is a balance between adaptation, by reorganisation and organelle b...