The Effect of Cholesterol Content on the Adjuvant Activity of Nucleic-Acid-Free Lipid Nanoparticles

• Main Authors: Jessica Anindita (Author), Hiroki Tanaka (Author), Takuma Yamakawa (Author), Yuka Sato (Author), Chika Matsumoto (Author), Kota Ishizaki (Author), Taiji Oyama (Author), Satoko Suzuki (Author), Keisuke Ueda (Author), Kenjirou Higashi (Author), Kunikazu Moribe (Author), Kasumi Sasaki (Author), Yumika Ogura (Author), Etsuo Yonemochi (Author), Yu Sakurai (Author), Hiroto Hatakeyama (Author), Hidetaka Akita (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

RNA vaccines are applicable to the treatment of various infectious diseases via the inducement of robust immune responses against target antigens by expressing antigen proteins in the human body. The delivery of messenger RNA by lipid nanoparticles (LNPs) has become a versatile drug delivery system...