The Effects of Statin Dose, Lipophilicity, and Combination of Statins plus Ezetimibe on Circulating Oxidized Low-Density Lipoprotein Levels: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

• Main Authors: Tannaz Jamialahmadi (Author), Fatemeh Baratzadeh (Author), Željko Reiner (Author), Luis E. Simental-Mendía (Author), Suowen Xu (Author), Andrey V. Susekov (Author), Raul D. Santos (Author), Amirhossein Sahebkar (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Elevated plasma low-density lipoprotein cholesterol (LDL-C) is the main risk factor for atherosclerotic cardiovascular disease (ASCVD). Statins are the drugs of choice for decreasing LDL-C and are used for the prevention and management of ASCVD. Guidelines recommend that subjects with hi...