Olanzapine-induced lipid disturbances: A potential mechanism through the gut microbiota-brain axis

• Main Authors: Zhenyu Zhu (Author), Yuxiu Gu (Author), Cuirong Zeng (Author), Man Yang (Author), Hao Yu (Author), Hui Chen (Author), Bikui Zhang (Author), Hualin Cai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Long-term use of olanzapine can induce various side effects such as lipid metabolic disorders, but the mechanism remains to be elucidated. The gut microbiota-brain axis plays an important role in lipid metabolism, and may be related to the metabolic side effects of olanzapine. Therefore,...