PLGA Nanoparticle-Based Formulations to Cross the Blood-Brain Barrier for Drug Delivery: From R&D to cGMP

• Main Authors: Kaining Zhi (Author), Babatunde Raji (Author), Anantha R. Nookala (Author), Mohammad Moshahid Khan (Author), Xuyen H. Nguyen (Author), Swarna Sakshi (Author), Tayebeh Pourmotabbed (Author), Murali M. Yallapu (Author), Harry Kochat (Author), Erene Tadrous (Author), Shelby Pernell (Author), Santosh Kumar (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The blood-brain barrier (BBB) is a natural obstacle for drug delivery into the human brain, hindering treatment of central nervous system (CNS) disorders such as acute ischemic stroke, brain tumors, and human immunodeficiency virus (HIV)-1-associated neurocognitive disorders. Poly(lactic-<i>co...