Novel Pt(IV) prodrug self-assembled nanoparticles with enhanced blood circulation stability and improved antitumor capacity of oxaliplatin for cancer therapy

• Main Authors: Yuanlei Fu (Author), Ying Kong (Author), Xiangping Li (Author), Dongfang Cheng (Author), Yuqian Hou (Author), Yan Li (Author), Tongfang Li (Author), Yani Xiao (Author), Qiuyan Zhang (Author), Rong Rong (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractPt(IV) compounds are regarded as prodrugs of active Pt(II) drugs (i.e. cisplatin, carboplatin, and oxaliplatin) and burgeoned as the most ideal candidates to substitute Pt(II) anticancer drugs with severe side effects. Nanoparticle drug delivery systems have been widely introduced to deliver...