Ginsenoside F1 Ameliorates Endothelial Cell Inflammatory Injury and Prevents Atherosclerosis in Mice through A20-Mediated Suppression of NF-kB Signaling

• Main Authors: Meng Qin (Author), Yun Luo (Author), Shan Lu (Author), Jing Sun (Author), Ke Yang (Author), Guibo Sun (Author), Xiaobo Sun (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2017-12-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Atherosclerosis (AS) is a chronic inflammatory disease and endothelial cell injury is the initial event. In this study, we investigated the protective effects of ginsenoside F1 (GF1) on AS and the potential molecular mechanisms of ox-LDL induced endothelial injury. ApoE-/- mice were fed a high fat d...