Comparative Evaluation of Calcium-Sensitizing Agents, Pimobendan and SCH00013, on the Myocardial Function of Canine Pacing-Induced Model of Heart Failure

• Main Authors: Lina Hamabe (Author), Keisuke Kawamura (Author), Soo-min Kim (Author), Rieko Yoshiyuki (Author), Toshiharu Fukayama (Author), Miki Shimizu (Author), Ryuji Fukushima (Author), Ryo Tanaka (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pimobendan and SCH00013 are calcium sensitizers that possess dual action of calcium sensitization and phosphodiesterase-III inhibition. This study was conducted to comparatively evaluate the effect of these medications on the myocardial function of the canine pacing-induced heart failure model using...