Itraconazole Loaded Biosurfactin Micelles with Enhanced Antifungal Activity: Fabrication, Evaluation and Molecular Simulation

• Main Authors: Faisal Usman (Author), Mudassir Farooq (Author), Tanveer A. Wani (Author), Hassan Ahmad (Author), Ibrahim Javed (Author), Mazhar Iqbal (Author), Fatima Akbar Sheikh (Author), Farhan Siddique (Author), Seema Zargar (Author), Saleh Sheikh (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Itraconazole (ITZ) is a broad-spectrum antifungal for superficial subcutaneous and systemic fungal infections. This study aimed to enhance the antifungal activity of ITZ using surfactin A (SA), a cyclic lipopeptide produced by the SA-producing <i>Bacillus</i> strain NH-100, possessing st...