Development of a preliminary in vitro drug screening assay based on a newly established culturing system for pre-adult fifth-stage Onchocerca volvulus worms.

• Main Authors: Denis Voronin (Author), Nancy Tricoche (Author), Shabnam Jawahar (Author), Michael Shlossman (Author), Christina A Bulman (Author), Chelsea Fischer (Author), Michael T Suderman (Author), Judy A Sakanari (Author), Sara Lustigman (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The human filarial parasite Onchocerca volvulus is the causative agent of onchocerciasis (river blindness). It causes blindness in 270,000 individuals with an additional 6.5 million suffering from severe skin pathologies. Current international control programs focus on the reduction of mi...