The Prophylactic Effect of Pinocembrin Against Doxorubicin-Induced Cardiotoxicity in an In Vitro H9c2 Cell Model

• Main Authors: Nonhlakanipho F. Sangweni (Author), Malebogo Moremane (Author), Sylvia Riedel (Author), Derick van Vuuren (Author), Barbara Huisamen (Author), Lawrence Mabasa (Author), Reenen Barry (Author), Rabia Johnson (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundThe clinical use of Doxorubicin (Dox) is significantly limited by its dose-dependent cardiotoxic side effect. Accumulative evidence suggests that the use of flavonoids, such as the antioxidative Pinocembrin (Pin), could be effective in the prevention of Dox-induced cardiotoxicity. Accordin...