No neuroprotective effect of therapeutic hypothermia following lipopolysaccharide-sensitized hypoxia-ischemia: a newborn piglet study

• Main Authors: Mads Andersen (Author), Hannah Brogård Andersen (Author), Ted Carl Kejlberg Andelius (Author), Lærke Hjøllund Hansen (Author), Regitze Pinnerup (Author), Mette Bjerre (Author), Steffen Ringgaard (Author), Leslie Schwendimann (Author), Pierre Gressens (Author), Kasper Jacobsen Kyng (Author), Tine Brink Henriksen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionTherapeutic hypothermia is the only proven neuroprotective treatment for hypoxic-ischemic encephalopathy. However, studies have questioned whether therapeutic hypothermia may benefit newborns subjected to infection or inflammation before a hypoxic-ischemic insult. We aimed to compare new...