Spironolactone hyaluronic acid enriched cerosomes (HAECs) for topical management of hirsutism: in silico studies, statistical optimization, ex vivo, and in vivo studies

Spironolactone hyaluronic acid enriched cerosomes (HAECs) for topical management of hirsutism: in silico studies, statistical optimization, ex vivo, and in vivo studies

Spironolactone (SP) is a potassium sparing diuretic with antiandrogenic properties. This study aimed at formulating SP into hyaluronic acid enriched cerosomes (HAECs) for topical management of hirsutism. HAECs were prepared by ethanol injection method, according to D-optimal design, after a proper i...

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Bibliographic Details
Main Authors: Rofida Albash (Author), Abdurrahman M. Fahmy (Author), Mohammed I.A. Hamed (Author), Khaled M. Darwish (Author), Rania Moataz El-Dahmy (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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