Spironolactone hyaluronic acid enriched cerosomes (HAECs) for topical management of hirsutism: in silico studies, statistical optimization, ex vivo, and in vivo studies

• Main Authors: Rofida Albash (Author), Abdurrahman M. Fahmy (Author), Mohammed I.A. Hamed (Author), Khaled M. Darwish (Author), Rania Moataz El-Dahmy (Author)
• Format: Knjiga
• Izdano: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Spironolactone (SP) is a potassium sparing diuretic with antiandrogenic properties. This study aimed at formulating SP into hyaluronic acid enriched cerosomes (HAECs) for topical management of hirsutism. HAECs were prepared by ethanol injection method, according to D-optimal design, after a proper i...