Clinical evaluation of PF614, a novel TAAP prodrug of oxycodone, versus OxyContin in a multi‐ascending dose study with a bioequivalence arm in healthy volunteers
Abstract PF614, a trypsin‐activated abuse protection oxycodone prodrug designed to reduce recreational drug abuse, was compared to OxyContin for safety and pharmacokinetics (PKs) of plasma oxycodone following oral administration. This study was a two‐part design including a multi‐ascending dose (par...
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Main Authors: | , , , , , , |
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Format: | Book |
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Wiley,
2024-03-01T00:00:00Z.
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Internet
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A1234.567 |
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Copy 1 | Available |