Clinical evaluation of PF614, a novel TAAP prodrug of oxycodone, versus OxyContin in a multi‐ascending dose study with a bioequivalence arm in healthy volunteers

Abstract PF614, a trypsin‐activated abuse protection oxycodone prodrug designed to reduce recreational drug abuse, was compared to OxyContin for safety and pharmacokinetics (PKs) of plasma oxycodone following oral administration. This study was a two‐part design including a multi‐ascending dose (par...

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Bibliographic Details
Main Authors: D. Lynn Kirkpatrick (Author), Cari Evans (Author), Linda A. Pestano (Author), Jeffrey Millard (Author), Matthew Johnston (Author), Emily Mick (Author), William K. Schmidt (Author)
Format: Book
Published: Wiley, 2024-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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