Aging Induced p53/p21 in Genioglossus Muscle Stem Cells and Enhanced Upper Airway Injury

• Main Authors: Lu-Ying Zhu (Author), Li-Ming Yu (Author), Wei-Hua Zhang (Author), Jia-Jia Deng (Author), Shang-Feng Liu (Author), Wei Huang (Author), Meng-Han Zhang (Author), Yan-Qin Lu (Author), Xin-Xin Han (Author), Yue-Hua Liu (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aging of population brings related social problems, such as muscle attenuation and regeneration barriers with increased aging. Muscle repair and regeneration depend on muscle stem cells (MuSCs). Obstructive sleep apnea (OSA) rises in the aging population. OSA leads to hypoxia and upper airway muscle...