Single-cell RNA-sequencing reveals a distinct population of proglucagon-expressing cells specific to the mouse upper small intestine
Objectives: To identify sub-populations of intestinal preproglucagon-expressing (PPG) cells producing Glucagon-like Peptide-1, and their associated expression profiles of sensory receptors, thereby enabling the discovery of therapeutic strategies that target these cell populations for the treatment...
Saved in:
Main Authors: | Leslie L. Glass (Author), Fernando J. Calero-Nieto (Author), Wajid Jawaid (Author), Pierre Larraufie (Author), Richard G. Kay (Author), Berthold Göttgens (Author), Frank Reimann (Author), Fiona M. Gribble (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2017-10-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells
by: Helen Soedling, et al.
Published: (2015) -
The Peutz-Jeghers kinase LKB1 suppresses polyp growth from intestinal cells of a proglucagon-expressing lineage in mice
by: Sagen Zac-Varghese, et al.
Published: (2014) -
Small RNA sequencing reveals distinct nuclear microRNAs in pig granulosa cells during ovarian follicle growth
by: Derek Toms, et al.
Published: (2021) -
Mechanistic insights into the detection of free fatty and bile acids by ileal glucagon-like peptide-1 secreting cells
by: Deborah A. Goldspink, et al.
Published: (2018) -
Co-storage and release of insulin-like peptide-5, glucagon-like peptide-1 and peptideYY from murine and human colonic enteroendocrine cells
by: Lawrence J. Billing, et al.
Published: (2018)