Development of Multilayer Nanoparticles for the Delivery of Peptide-Based Subunit Vaccine against Group A <i>Streptococcus</i>

• Main Authors: Jolynn Kiong (Author), Ummey Jannatun Nahar (Author), Shengbin Jin (Author), Ahmed O. Shalash (Author), Jiahui Zhang (Author), Prashamsa Koirala (Author), Zeinab G. Khalil (Author), Robert J. Capon (Author), Mariusz Skwarczynski (Author), Istvan Toth (Author), Waleed M. Hussein (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Peptide-based subunit vaccines include only minimal antigenic determinants, and, therefore, are less likely to induce allergic immune responses and adverse effects compared to traditional vaccines. However, peptides are weakly immunogenic and susceptible to enzymatic degradation when administered on...