Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles

• Main Authors: Christophe Delehedde (Author), Luc Even (Author), Patrick Midoux (Author), Chantal Pichon (Author), Federico Perche (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Messenger RNA (mRNA) is being extensively used in gene therapy and vaccination due to its safety over DNA, in the following ways: its lack of integration risk, cytoplasmic expression, and transient expression compatible with fine regulations. However, clinical applications of mRNA are limited by its...