Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles

• Egile Nagusiak: Christophe Delehedde (Egilea), Luc Even (Egilea), Patrick Midoux (Egilea), Chantal Pichon (Egilea), Federico Perche (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Messenger RNA (mRNA) is being extensively used in gene therapy and vaccination due to its safety over DNA, in the following ways: its lack of integration risk, cytoplasmic expression, and transient expression compatible with fine regulations. However, clinical applications of mRNA are limited by its...