Carbonic Anhydrase 1-Mediated Calcification Is Associated With Atherosclerosis, and Methazolamide Alleviates Its Pathogenesis

• Main Authors: Lin Yuan (Author), Minghua Wang (Author), Tianqi Liu (Author), Yinsheng Lei (Author), Qiang Miao (Author), Quan Li (Author), Hongxing Wang (Author), Guoqing Zhang (Author), Yinglong Hou (Author), Xiaotian Chang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vascular calcification is an important pathogenic process in atherosclerosis (AS); however, its immediate cause is unknown. Our previous study demonstrated that carbonic anhydrase 1 (CA1) stimulates ossification and calcification in ankylosing spondylitis and breast cancer. The current study investi...