Safety, Tolerability, and Pharmacokinetics of a Novel Mitochondrial Modulator, TRC150094, in Overweight and Obese Subjects: A Randomized Phase-I Clinical Trial

• المؤلفون الرئيسيون: Deepa Joshi (مؤلف), Prashant Jamadarkhana (مؤلف), Suchit Kumbhare (مؤلف), Amarinder Singh (مؤلف), Jignesh Kotecha (مؤلف), Deepak Bunger (مؤلف), Ajay Shiwalkar (مؤلف), Anookh Mohanan (مؤلف), Chaitanya Dutt (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

TRC150094, a novel mitochondrial modulator, can restore metabolic flexibility by improving insulin resistance in preclinical studies. This study primarily aims to evaluate the safety, tolerability, and pharmacokinetics (PK) of oral TRC150094 after conducting two double-blind, randomized, Phase-I stu...