Safety, Tolerability, and Pharmacokinetics of a Novel Mitochondrial Modulator, TRC150094, in Overweight and Obese Subjects: A Randomized Phase-I Clinical Trial

• Κύριοι συγγραφείς: Deepa Joshi (Συγγραφέας), Prashant Jamadarkhana (Συγγραφέας), Suchit Kumbhare (Συγγραφέας), Amarinder Singh (Συγγραφέας), Jignesh Kotecha (Συγγραφέας), Deepak Bunger (Συγγραφέας), Ajay Shiwalkar (Συγγραφέας), Anookh Mohanan (Συγγραφέας), Chaitanya Dutt (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

TRC150094, a novel mitochondrial modulator, can restore metabolic flexibility by improving insulin resistance in preclinical studies. This study primarily aims to evaluate the safety, tolerability, and pharmacokinetics (PK) of oral TRC150094 after conducting two double-blind, randomized, Phase-I stu...