Safety, Tolerability, and Pharmacokinetics of a Novel Mitochondrial Modulator, TRC150094, in Overweight and Obese Subjects: A Randomized Phase-I Clinical Trial

• Үндсэн зохиолчид: Deepa Joshi (Зохиогч), Prashant Jamadarkhana (Зохиогч), Suchit Kumbhare (Зохиогч), Amarinder Singh (Зохиогч), Jignesh Kotecha (Зохиогч), Deepak Bunger (Зохиогч), Ajay Shiwalkar (Зохиогч), Anookh Mohanan (Зохиогч), Chaitanya Dutt (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

TRC150094, a novel mitochondrial modulator, can restore metabolic flexibility by improving insulin resistance in preclinical studies. This study primarily aims to evaluate the safety, tolerability, and pharmacokinetics (PK) of oral TRC150094 after conducting two double-blind, randomized, Phase-I stu...