Safety, Tolerability, and Pharmacokinetics of a Novel Mitochondrial Modulator, TRC150094, in Overweight and Obese Subjects: A Randomized Phase-I Clinical Trial

• Главные авторы: Deepa Joshi (Автор), Prashant Jamadarkhana (Автор), Suchit Kumbhare (Автор), Amarinder Singh (Автор), Jignesh Kotecha (Автор), Deepak Bunger (Автор), Ajay Shiwalkar (Автор), Anookh Mohanan (Автор), Chaitanya Dutt (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Предметы: article
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TRC150094, a novel mitochondrial modulator, can restore metabolic flexibility by improving insulin resistance in preclinical studies. This study primarily aims to evaluate the safety, tolerability, and pharmacokinetics (PK) of oral TRC150094 after conducting two double-blind, randomized, Phase-I stu...