Virtual Screening-Based Study of Novel Anti-Cancer Drugs Targeting G-Quadruplex

• Main Authors: Ruizhuo Ouyang (Author), Jinyao Liu (Author), Shen Wang (Author), Weilun Zhang (Author), Kai Feng (Author), Conghao Liu (Author), Baolin Liu (Author), Yuqing Miao (Author), Shuang Zhou (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In order to develop new anti-cancer drugs more efficiently and reduce side effects based on active drug targets, the virtual drug screening was carried out through the target of G-quadruplexes and 23 hit compounds were, thus, screened out as potential anticancer drugs. Six classical G-quadruplex com...