Virtual Screening-Based Study of Novel Anti-Cancer Drugs Targeting G-Quadruplex

• Asıl Yazarlar: Ruizhuo Ouyang (Yazar), Jinyao Liu (Yazar), Shen Wang (Yazar), Weilun Zhang (Yazar), Kai Feng (Yazar), Conghao Liu (Yazar), Baolin Liu (Yazar), Yuqing Miao (Yazar), Shuang Zhou (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2023-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

In order to develop new anti-cancer drugs more efficiently and reduce side effects based on active drug targets, the virtual drug screening was carried out through the target of G-quadruplexes and 23 hit compounds were, thus, screened out as potential anticancer drugs. Six classical G-quadruplex com...