Dendrimer-based posaconazole nanoplatform for antifungal therapy

• Main Authors: Shengzhuang Tang (Author), Jesse Chen (Author), Jayme Cannon (Author), Zhengyi Cao (Author), James R. Baker (Author), Su He Wang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We examined formulating a new antifungal agent, posaconazole (POS) and its derivatives, with different molecular vehicles. Several combinations of drug and carrier molecules were synthesized, and their antifungal activities were evaluated against Aspergillus fumigatus. Posaconazole and four of its d...