Intracerebroventricular administration of oxytocin and intranasal administration of the oxytocin derivative improve β‐amyloid peptide (25-35)‐induced memory impairment in mice

• Main Authors: Junpei Takahashi (Author), Yudai Ueta (Author), Daisuke Yamada (Author), Sachie Sasaki‐Hamada (Author), Takashi Iwai (Author), Tomomi Akita (Author), Chikamasa Yamashita (Author), Akiyoshi Saitoh (Author), Jun‐Ichiro Oka (Author)
• Format: Book
• Published: Wiley, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Aim We previously reported that oxytocin, a peptide hormone, can reverse the β‐amyloid peptide (25-35) (Aβ25-35)‐induced impairments of the murine hippocampal synaptic plasticity. In this study, we examined the effects of oxytocin on the Aβ25-35‐induced impairment of cognitive behavior in m...